Tomorrow's technologies will come from knowledge gained today. This is why the Arizona Heart Institute is an avid supporter of cardiovascular research that enables the medical community to determine whether new treatments are safe and effective for a particular medical condition. At any given time, we are directly involved in the development of exciting new technologies, non-invasive medical devices, revolutionary drug therapies and groundbreaking surgical and interventional techniques. Such research programs have produced results which continue to have a significant impact on the lives of those patients at risk of or suffering from heart and vascular conditions.

The following list summarizes enrolling and upcoming clinical research studies at the Arizona Heart Institute.

Enrolling Studies:

REVIVE Study - A multicenter, randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy, safety, and tolerability of Ixmyelocel-T in subjeccts with critical limb ischemia and no options for revascularization.

VENTANA Study - Prospective, Multicenter, Single Arm Safety and Effectiveness Trial of the Endologix Fenestrated Stent Graft System for the Endovascular Repair of Juxtarenal/Pararenal (JAA/PAA) Aneurysms. Learn More.

EASE Study - “Endovascular Atherectomy Safety and Effectiveness (EASE) Study" - - A Prospective, Multicenter Clinical Evaluation of the Safety and Effectiveness of the Phoenix Atherectomy™ System in Atherectomy of the Peripheral Vasculature.

Endoform Study - Wound Fluid Protease Levels During Use of Endoform Dermal Template - - A randomized, unblinded, multi-center, repeated measure study of males and females with venous leg ulcer wounds with duration of one year or less.

FSS OPEN - Evaluation of Safety and Efficacy of the FlexStent® Femoropopliteal Self-Expanding Stent System Study.

RELAY - A phase II clinical study of the safety and efficacy of the relay thoracic stent graft in patients with thoracic aortic pathologies.

Jetstream G3™ Calcium Study - A Prospective, Single-Arm Study to Evaluate the Effects of the Jetstream G3/ Navitus System on Calcified Peripheral Vascular Lesions.

PMX-60056 - A Phase 2 Proof of Concept Study of PMX-60056 for the Reversal of Heparin in Patients Undergoing Percutaneous Coronary Intervention.

ANACONDA - The Vascutek Anaconda Stent Graft System Phase II IDE Study (infrarenal abdominal aortic aneurysm).

EXCITE - EXCImer Laser Randomized Controlled Study for Treatment of FemoropopliTEalInStent Restenosis: A prospective, multicenter, study with a randomized controlled trial (RCT) component and a Total Occlusion Registry (TO) component.

Upcoming Studies:

Refractory Chronic Myocardial Ischemia - A Prospective, Randomized, Double-Blinded, Active-Control and Unblinded Standard of Care (SOC) Controlled Study to Determine the Efficacy and Safety of Targeted Intramyocardial Delivery of G-CSF Mobilized Autologous CD34+ Cells for the Improvement in Total Exercise Time during Standardized Exercise Testing in Subjects with Refractory Angina Pectoris and Chronic Myocardial Ischemia (CMI).

INSPIRATION - AAA Stent Graft System - A Multicenter, Open Label, Prospective, Non-Randomized Study Of The INCRAFT™ Stent Graft System In Subjects With Abdominal Aortic Aneurysms.

The JET Registry - Jetstream NAVITUS System Endovascular Therapy Post-market Registry:  Multicenter, open label, multiple-group assignment, non-randomized registry of up to 500 patients.

ANCHOR - Aneurysm Treatment using the HeliFXAoritic Securement System Global Registry - use of a FDA clearnedHeliFX device.

IN.PACT SFA - Randomized Trial of IN.PACT (Paclitaxel) Admiral Drug-Eluting Balloon (DEB) vs Standard PTA for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery (SFA) and/or Proximal Popliteal Artery (PPA).